Season 6 follows immediately after the 5th season of the show. It takes place in Hokkaido, Japan, where the theme changes from Horror Special to Fruits Special.

In a prologue, the cast is introduced to the settings and suspects of a murder case for the new episode. The cast then chooses their role in the episode, as a particular suspect or the detective. Other than the detective, each person is given detailed information about the suspect they are portraying including their personalities, alibi, relationship to the victim and other suspects, history, criminal motive, etc. Every suspect can conceal information until explicitly questioned by other suspects or the detective, but only the criminal can lie.

The show follows South Korean and foreign cast members of the South Korean television Non-Summit as they experience cultures of various countries through homestay, meeting the locals, and experiencing a better understanding of multiculturalism.

People who overcome life's hardship must have a secret that improves their lives. The Counter Punch, a new life information show, follows those who have successfully overcome economic and health problems and have a second chance in life.

Dads observed their daughter's love process with the hosts.

In the sixth season of NCT Life series, the members of NCT go touring Chiang Mai during their time in Thailand.

VIXX members are equipped with cameras and go on different missions every week.

Baek Jong Won's Alley Restaurant is a South Korean cooking-variety program. It is a spin-off of cooking-variety program Baek Jong Won's Top 3 Chef King. Mr. Baek come in a target alley and help few restaurant owners to improve the quality of main dishes in their menu for customers' attracting.