Duan Fei is a Special Forces agent who marries Yun Shi Tong, yet their marriage is only a cover to better protect Shi Tong from the assassination attempts against her life.

"22 Flower Road" is a webdrama about young people who share what they have and do not have with each other and become adults. It is expected to bring about realistic empathy with its highlights through the youthful lives of five young people.

Shogo Higuchi is a detective whose wife was murdered by a serial killer. Hikari Tachibana is a voice profiler whose father was murdered. She has a special hearing ability which allows her to hear minutiae sounds that other people do not. Victims in criminal cases call #110 which is connected to the emergency control room. To save people as quickly as possible, an investigation "emergency call response unit" is formed. Hikari Tachibana works in the emergency control room and gathers location information from callers with her special hearing ability. She passes on the information to Detective Shogo Higuchi in the emergency call response unit. Detective Shogo Higuchi then goes out with his team to save the victims. They must respond as quickly as possible during a crime's golden hour.

Contract worker Lee Yeon Seo daydreams about teaching her manager a lesson, but accidentally acts out her fantasy on none other than top Hallyu star Kang Joon Hyuk. Thinking she killed him but afraid to be labeled a murderer, she takes him home and prepares to get rid of the body. But Joon Hyuk wakes up and seeing her preparations thinks he has been kidnapped by a murderous psychopath. Seeing no other option, she keeps him hostage so he doesn't turn her in to the police. How long can she keep him hidden and can she ever convince him she's not an evil person?

The chain of flowers between Rinka, Miyuki and Satsuki become connected as secrets become revealed.

Rinka (Nao Matsushita) lost her parents 13 years ago in an accident. Since then, she has lived with her grandmother. Her grandmother is then diagnosed with stomach cancer and becomes hospitalized. Making things worse for Rinka, the English institute where she works goes bankrupt. Paying for her grandmother's surgery seems nearly impossible.

Rinka then thinks of K. K sends a bouquet of flowers every year. Rinka thinks if she can find K, that person might help her. But who is K? Rinka asks her grandmother about K, but her grandmother doesn't say anything. Rinka then sends a letter to K and, later, a man who identifies himself as K's secretary appears in front of her. Rinka tries to find out K's identity and why he keeps sending flowers.

Miyuki (Miki Nakatani) married Kazuya 3 years ago. Kazuya worked for her uncle's company. The only thing Miyuki worries about is that they don't have children yet.

Kazuya's dream was to become an architect, but he now works in the sales department for an architect firm run by his wife's cousin Yosuke. Kazuya then participates in a competition to design an art gallery. Kazuya wins the competition, but Yosuke placed his name on Kazuya's design.

After Miyuki complains to Yosuke about his actions, Kazuya tells her something that has been on his mind. This causes tragedy.

University student Satsuki (Erika Toda) joins a climbing club with her friend Kimiko. Satsuki falls in love with Koichi who is in the same club. When Satsuki views Kocihi as part of her fate, Kurata, from the climbing club, collapses from leukemia.

Satsuki and Koichi take a test of their white blood cells. Satsuki finds out that she has the same white blood cell forms as Kocihi. A shocking hidden truth is reveled.

Here comes the story of a heart-warming and down-to-earth modern family! Duk Hwa, a former celebrity who married a hot wife who is 20 years younger than him. Keum Pyo, a first-born daughter in her second marriage after a failure of her first. Eun Pyo, a second daughter who's down-to-earth and born to love a man. Dong Pyo, a bigmouth phony-baloney living his restless youth. These outrageous members reveal their stories as their family feud unfolds.