Riam is a beautiful woman who's always been unlucky in love. After three failed relationships, she vows that love and marriage is bogus. One drunken night, she stumbles back to her apartment but mistakenly goes into her new neighbor’s apartment instead, Ongsa. He is her childhood classmate that she teased relentless because he was pimply faced and refused to help her cheat on tests. Ongsa, many years later, is an established chef who has clear skin and no glasses. Though Riam doesn’t recognize him immediately, Ongsa knows which pretty face he’s staring at.

The next day, Riam collapses during a work meeting because of Chocolate Cyst, which is an ovarian endometrioma, a fluid filled cyst that forms in her ovaries. The doctor relents that there are two prognoses. The first one is to have surgery, but there’s a chance that it may return. The second option is to have a baby. Pregnancy lowers the risk. At first Riam doesn’t think her condition would likely escalate, but cancer is hereditary in her family, which makes her diagnosis even more grim. So Riam decides she shall go husband hunting and kick potential cancer to the curb.

No matter how hard he thinks about it, Todoin Seiya cannot figure out why he doesn’t have a girlfriend in his 16-year lifespan. Physically attractive, naturally smart, athletic and, on top of that, comes from a wealthy and politically significant family. And it’s not like he hasn’t tried either, but every girl he asks out flat out rejects him. Seiya sets a goal for himself to get a girlfriend by the time high school ends and rejection isn’t going to stop him from trying again. But it sure is heartbreaking when you get rejected this many times without knowing why.

Goro Zaizen and Shuji Satomi are assistant professors at Naniwa University Hospital. Goro is a brilliant surgeon who will do anything to make his way up the corporate ladder. On the other hand, Shuji is a physician who earnestly devotes himself to medical research. Though the two doctors have contrasting personalities and are considered to be rivals, they highly recognize each other's skills. The entire medical department is restless while preparing for the election to choose a new Surgical Department Professor. All Goro has on his mind, is how to win the election. Meanwhile, Shuji is looking after a patient who apparently has pancreatic cancer. He carries out tests on the patient cautiously, and is very careful in telling the patient of the cancer. However, Goro barges in on their conversation, and out of the blue, tells the patient he has cancer, and that he needs an operation right away. Shuji is furious at Goro's rude attitude, and yells, "Doctors are not God!" Goro ignores this, and starts laying the groundwork for the operation. But when Goro finds out that the Director of the Medical Department has already given a diagnosis of stomach cancer, he cancels the operation. He feels that pointing out his boss's misdiagnosis will only hurt him in the upcoming election. Shuji however, is determined to save the patient's life and go on with the operation.

Ito Misaki stars as the number-one cabaret/hostess club girl. Hailing from the Miyazaki countryside, she has been told since her youth that all she has is a beautiful face. Her brilliant younger brother (played by Moriyama Mirai) who aims to become a doctor, is her only pride. For his sake, she is willing to put up with all sorts of hardships in a display of unconditional love.

During the Anti-Japanese War, a group of highly trained female spies hold the key to defeating the enemies. Guo Chun Guang is a highly trained spy for the Communist Party who goes undercover as a dentist in Shanghai to gather intelligence on the enemies. Gu Xue Feng becomes the new Shanghai stationmaster for the Kuomintang (KMT) military regime and is tasked with forming an all-female special force known as Code Thirteen. Can Li Feng Huang lead Code Thirteen to intercept their enemies’ transmissions and win the war?

Ruco plays Luk Kung Ji, he's a Malaysian tour guide, loves to play and sweet talks, but his real job is a Hong Kong music producer. He fled to Malaysia because he broke up with girlfriend Hong Yi Kiu (Elaine Yiu), then met Law Sik Sik (Aimee Chan), who also fled to Malaysia because she broke up with her fiance Ching Jin Pok (Matt Yeung). Aimee becomes the head of the travel agency after going to Malaysia and meets Ruco there. They became a bickering couple and developed feelings, but Ruco still had a knot in his heart and so they were unable to develop further; Ching Jin Chan (Lin Xiawei) is a silly girl who easily falls in love. Because Ruco showed some care for her, she fell in love with him and later falls for dessert chef Chin Chun (Tony Hung) too. Since she loves desserts, she asked Tony to be her cooking teacher and later finds out he has a crush on Aimee. She captured it on video and used it to threaten Tony to fulfill 3 wishes for her; Tony and Aimee are best friends, like sisters, but Tony secretly loves her. He's a strict person and is a hardcore instructor to Lin Xiawei; Elaine is a singer-songwriter, dated Ruco before; Matt and Lin Xiawei are siblings, and Aimee's ex-fiance. In front of Aimee, he acts very loving and caring, but in fact he's a player. He cheated on her with Wong Kei Ying (Samantha Ko); Samantha was Aimee's good friend, but the intimate clips of her affair with Matt were exposed at Aimee and Matt's engagement party, the couple broke up instantly.

A tire comes off a moving truck and becomes a deadly weapon, hitting a mother and child. The problem was caused by the vehicle manufacturer's failure to recall the vehicle, but the blame falls on the head of the delivery company who, despairing, searches for evidence that the recall was suppressed. Crossing paths with banks, police, weekly magazine writers, the victim's family, and various others, he eventually gets to the truth of the matter.