Manga artist Yuichi Okano begins writing nurse notes while taking care of his mother, who is afflicted with Alzheimer's disease.

Underneath the veneer of orderly lives, frozen smiles and awkward averted glances, SWEET LITTLE LIES is a cold-as-steel clinical study of a couple. Married for three years, the couple keeps up the apparently tender rituals of newlyweds, but all is not as bright and beautiful as it would seem. Miki Nakatani, “the best Japanese actress of her generation” (Mark Schilling, Japan Times) plays the emotionally and sexually starved wife in Hitoshi Yazaki’s anti-melodramatic chronicle of the disintegration of a marriage. Even the most seasoned viewers will be struck by the menacing calm of Yazaki’s compositions, and his unveiling of lives made from lies.

Seiji (Masanobu Ando) is a third generation "Gosei kai" gang member. He works to build up the group's strength. Meanwhile, a journalist (Tasuku Emoto) investigates a case that occurred 19 years ago. He meets Hayato (Masahiro Higashide), Daisuke (Kenta Kiritani)...

1933. 20 years before, Katsuzo was in love with a geisha who gave him a daughter. They tried to run away together but they were caught and the woman was killed under his eyes. Now he is a zegen aka a pimp who sells girls to the Yokiro, the biggest geisha house in Southern Japan, run by Osode who used to be his mistress. His daughter who was raised by the Geisha House is now a Great Geisha under the name Momowaka. And his girlfriend, Tamako, wants to become a geisha. Momowaka falls in love, one of Osaka's yakuza clans wants to take control of the Yokiro.

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In Akihabara, Sakuragi Sakura runs cat cafe "Mocha." She listens to her customers’ troubles there. The various customers that enter her cafe also take comfort in the cats that reside there.

Adolescence is like a heavy rain. Even though you catch a cold from it, you still look forward to experiencing it once again. Ko-Teng has several close friends who had a crush on Shen Chia-Yi. Those friends of Ko's thus moved in unison from Ching Chengs junior high school straight into the senior high school division in pursuit of her. Naughty in nature, Ko was ordered by their homeroom teacher to sit in front of honor student Shen for her to keep close tabs on him. The two hadn't hit it off at first but Ko gradually fell for Shen, who was always pressuring him to study hard. On the other hand, Shen became impressed by the contrasting values Ko represented. Ko started pursuing Shen but Shen remained hesitant.