Ji Seung Yeon dreams of becoming a hip-hop legend and unexpected events set her on the path to achieve just that, although there is an added obstacle - she has to dress up as a boy in order to join a male idol group. In the process, she meets Kang Woo Hyun, the leader of the popular idol group, M2, who captivates fans with a killer smile that masks his rude and selfish personality.

Following his late teacher’s passing, Jin Shiyi (Raymond Lam) leaves Snake Island for the Central Plains in search of Mang Shan Sect’s Lü Si Niang (Bai Yin) to pass her a letter and to request her help in purging the poison in his body. Upon his arrival in the Central Plains, the innocent Shiyi becomes an unwilling participant in the tumultuous world of martial arts and battles. Because of the ragged clothes he is wearing, Shiyi is mistaken for a member of the Beggar's Sect and is dragged into their battles with the Shaolin Monks. There, he meets Li Shengnan (Michelle Ye), an assassin sent by the Emperor’s lackey Simen Muyi to break up the unity between the sects, and Gu Zhihua (Rain Li), Lü Si Niang’s disciple. Lü Si Niang dies in her attempt to save Shiyi, leaving Mang Shan Sect to believe Shiyi is the murderer. Disillusioned by the turn of events, Zhihua joins Shiyi in his wanders. Shengnan, dedicated to seek revenge against Shiyi, joins them but unwittingly falls in love with Shiyi. Sensing the attraction between Zhihua and Shiyi, Shengnan continually harasses and creates problems for Zhihua. They arrive at Volcano Island to obtain a precious martial arts manual but Zhihua is captured by the highly-skilled Meng Shen Tong, who manages to grab half of the manual and master the demonic gongfu. Shiyi and Shengnan pursue them back to the Central Plains, only to find the martial arts world in chaos. They wait for their chance to save the sect leaders and rid the world of Meng Shen Tong and Simen Muyi…

Saburo (Hiroki Hasegawa) works at a medical office on The Izu Islands, which has seen its population dwindle over the years. Even though Saburo doesn't have a medical license, he performs operations under the instructions of Dr. Muraki (Kohei Otomo). Because of his gifted dexterity and sincerity, people call him the Young Doctor. Saburo becomes conflicted over his position, but he convinces himself that what he is doing is helping people. Saburo becomes is also loved by nurse Akiko Suzuki (Izumi Inamori) and Akiko Tasaka (Fumino Kimura), who is the daughter of the director of a general hospital in Tokyo.

"22 Flower Road" is a webdrama about young people who share what they have and do not have with each other and become adults. It is expected to bring about realistic empathy with its highlights through the youthful lives of five young people.

Mal Ja, who is a part-time worker at a PR company, loves all living creatures but has experienced trauma with horses. Pebbles, her best friend, would like her to be something more and feels threatened by the arrival of a jockey who shows interest in Mal Ja.

Kusunoki Taketo is a single 30-year old dentist. A playboy, he will hit on all his female patients. Chigusa is a 24-year old typical OL, her only objective in life is to snare a wealthy and good-looking man for a husband. However, Chigusa's reputation precedes her, and is looked down upon by other OL, for being so obvious and tenacious in her search for a man. On one of her date with a eligible man from the company next door, she wins a holiday for two to Bali. It is here in Bali that she has a one night stand with Taketo.

After their one night together, while sightseeing in Bali, Taketo is reunited with his first love, Aya. She is a famous model, and is in Bali, holidaying with her latest boyfriend. Taketo had loved Aya deeply, but she was more interested in pursuing her dream of becoming a model. She had left him for another man, who had promised to launch her modelling career.

Upon their return to Tokyo, everyone goes their separate way. However, Chigusa is one day reunited with Taketo, when she goes to his clinic to fix her terrible toothache.