A daily drama about the crises in the life of a middle-aged couple. Lee Hae Joo is a dedicated homemaker who has already forgotten her dreams and self-value after years of marriage to her salaryman husband, Park Dae Sung. Everything, from his character, tastes, habits, and outlook on life clashes with hers, and she regrets not noticing this sooner. If Dae Sung's apathetic attitude, laziness and general disinterest wasn't unbearable enough, he is also having an affair with his co-worker, Bae Yoo Mi.
Jejoongwon is the first modern hospital in Korea established in the Joseon era in 1885. Baek Do Yang is a nobleman who gives up his status to enter its ranks. Hwang Jung is a butcher's son who becomes a physician, while Seok Ran enters Jejoongwon as an interpreter but takes on medical training to become a doctor.
Lee Jang Suk spent some time in a juvenile detention center for stealing wallets from unsuspecting strangers. After he gets out, he meets a sports agent, Nam Jae Il, who's trying to recover from a downfall in his carrier. Together, they work to achieve their dreams. Jang Suk dreams of becoming a K-1 Champion; and Nam Jae Il dreams of regaining his reputation as a top sports agent.