Yoo Se Poong’s legendary abilities as a physician are well-known in the royal palace. Nonetheless, he was expelled from the royal court when his involvement in a conspiracy against the royal family came to light. He moves and begins work in the strange, but, beautiful, Gyesu Village.
There he meets Kye Ji Han, Sorak Village’s grumpy old doctor with the heart of gold. Upon the encounter with Yoo Se Poong, Kye Ji Han is motivated to transform the young doctor into one who heals hearts.
Another resident of the village is Seo Eun Woo, who hails from a noble family and has keen observational skills and deep empathy. Now a widow, she mirrors the stories of the heartbroken. She feels wronged by her sudden marriage and is about to become an unwilling wife who stays virtuous to a deceased husband.
Adapted from the novel "Joseon Psychiatrist Yoo Se Pung" (조선 정신과 의사 유세풍) by Lee Eun So (이은소).
Leaning on each other through thick and thin, a trio of best friends stand together as they experience life, love and loss on the brink of turning 40.
Cha Mi Jo is the head dermatologist of a clinic in Gangnam. She is a warm character who grew up in a wealthy environment with a caring family and everything she could wish for.
Jung Chan Young dreamed of becoming an actress but ended up becoming an acting teacher instead. Although her way of speaking may seem blunt and harsh, the sincerity in her words makes her a character impossible to hate.
Jang Joo Hee is a department store cosmetics manager. Due to her timid personality, she has yet to really experience a romantic relationship.
At forty years old, Lee Boo Jeong has lost her way. She feels like she has reached the end of her potential and achieved absolutely nothing. Lee Kang Jae is twenty-seven, a man at the end of his youth, and though "afraid of nothing," feels afraid his life will never amount to anything.
"Lost" tells the story of ordinary people walking towards the light who suddenly realize that 'nothing has happened' in the middle of the downhill road of life. It depicts the most ordinary daily life standing on the edge of darkness rather than light, a life where one cannot easily choose.
